Enfamil
NeuroPro Infant
Our verdict
Enfamil's flagship is the easiest premium formula to actually prepare — it dissolves smoothly where Similac foams — and it's one of the only formulas with MFGM, a milk-fat component Mead Johnson has clinical research behind. The trade-offs: palm oil in the fat blend (a common suspect in firmer stools) and a top-shelf price.
Score breakdown
What's great
- One of the only mainstream formulas with added MFGM, backed by Mead Johnson clinical research
- 60:40 whey-to-casein ratio, closer to mature breast milk than most competitors
- Mixes easily with little to no foam (a consistent tester finding)
- Very widely available in many container sizes plus ready-to-feed
- Consumer Reports contaminant testing flagged Enfamil options among lower-risk formulas
Worth knowing
- Highest per-ounce price of the five ($1.73/oz at Walmart for the 28.3-oz can)
- Uses palm olein oil, which some studies and parents associate with firmer stools/constipation
- Some parents dislike the smell of the powder
- Contains soy oil
What's in it
| Protein | Nonfat milk and whey protein concentrate (60:40 whey-to-casein ratio) |
| Carbs | Lactose (plus prebiotic fibers polydextrose and GOS) |
| Fats | Palm olein, soy, coconut, and high oleic sunflower oils, plus single-cell DHA and ARA oils (includes palm oil) |
| Key features | MFGM (milk fat globule membrane) plus DHA - Mead Johnson's 'brain-building duo' · HuMO6 immune blend: triple prebiotic blend of 2'-FL HMO, GOS, and polydextrose (PDX) · Expert-recommended amount of omega-3 DHA · Iron-fortified · Non-GMO ingredients |
| Stage | 0-12 months |
| Forms | powder, ready-to-feed |
| Where to find it | Nationwide: Walmart, Target, Amazon, grocery and drug stores; 20.7 oz tubs, 28.3 oz value cans, 31.4 oz refill boxes, 36.6 oz XL cans, ready-to-feed bottles and 2-oz nursettes |
Note: ASIN B077M4Q27K is the 28.3-oz value can (seen in amazon.com/dp URL). Walmart sells the 28.3-oz can for $48.97 ($1.73/oz); NewModernMom measured about $1.38/oz at Costco club pricing, so per-oz cost varies significantly by retailer and size.
Best for
What parents say
Recurring themes we found across public parent discussions (Walmart.com customer reviews (products 274241484, 139955857), NewModernMom hands-on comparison (mixing/foam observations), TeachToddler Best Baby Formula 2026 ranking and Similac vs Enfamil comparisons, Forbes Health and Healthline best-formula roundups (2026), Note: direct r/FormulaFeeders threads did not surface in web search results; themes are from the public review sources above) — not reviews submitted on this site.
Loved
- Mixes smoothly with minimal foaming compared to Similac
- Babies tolerate it well and parents credit the MFGM/DHA marketing for choosing it
- Pediatrician recommendations frequently cited as the reason for choosing it
Common complaints
- Constipation and firmer stools reported by some parents (often attributed to palm olein); some switch to the Gentlease version
- Some babies get gassy on it
- Price - regularly described as expensive; parents watch for coupons and Enfamil Family Beginnings offers
- Unpleasant smell mentioned in reviews
Common questions
What is MFGM in Enfamil NeuroPro?
MFGM (milk fat globule membrane) is a component of milk fat naturally present in breast milk. Enfamil adds it alongside DHA and cites clinical studies on cognitive development — it's the brand's main differentiator from Similac.
Does Enfamil NeuroPro cause constipation?
Some parents report firmer stools or constipation, often attributed to the palm olein oil in its fat blend. It's not universal — many babies do fine — but if it persists, the Gentlease version or a palm-oil-free formula is a common next step discussed with pediatricians.
Is Enfamil NeuroPro worth the price versus store brands?
Store-brand formulas meet the same FDA standards for far less, but none currently match Enfamil's MFGM addition. Whether that specific ingredient justifies roughly triple the per-ounce price is the real question to weigh.
Reviews from parents like you
Real submissions from readers — moderated for spam, never edited for opinion.
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